13 March 2009 Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information
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Proceedings Volume 7258, Medical Imaging 2009: Physics of Medical Imaging; 72585C (2009) https://doi.org/10.1117/12.813815
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States
Abstract
In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Andrzej Krol, Levon Vogelsang, Yao Lu, Yuesheng Xu, Xiaofei Hu, Lixin Shen, David Feiglin, Edward Lipson, "Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information", Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72585C (13 March 2009); doi: 10.1117/12.813815; https://doi.org/10.1117/12.813815
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