Translator Disclaimer
3 March 2009 Breast tissue classification in digital breast tomosynthesis images using texture features: a feasibility study
Author Affiliations +
Proceedings Volume 7260, Medical Imaging 2009: Computer-Aided Diagnosis; 726024 (2009) https://doi.org/10.1117/12.813812
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States
Abstract
Mammographic breast density is a known breast cancer risk factor. Studies have shown the potential to automate breast density estimation by using computerized texture-based segmentation of the dense tissue in mammograms. Digital breast tomosynthesis (DBT) is a tomographic x-ray breast imaging modality that could allow volumetric breast density estimation. We evaluated the feasibility of distinguishing between dense and fatty breast regions in DBT using computer-extracted texture features. Our long-term hypothesis is that DBT texture analysis can be used to develop 3D dense tissue segmentation algorithms for estimating volumetric breast density. DBT images from 40 women were analyzed. The dense tissue area was delineated within each central source projection (CSP) image using a thresholding technique (Cumulus, Univ. Toronto). Two (2.5cm)2 ROIs were manually selected: one within the dense tissue region and another within the fatty region. Corresponding (2.5cm)3 ROIs were placed within the reconstructed DBT images. Texture features, previously used for mammographic dense tissue segmentation, were computed. Receiver operating characteristic (ROC) curve analysis was performed to evaluate feature classification performance. Different texture features appeared to perform best in the 3D reconstructed DBT compared to the 2D CSP images. Fractal dimension was superior in DBT (AUC=0.90), while contrast was best in CSP images (AUC=0.92). We attribute these differences to the effects of tissue superimposition in CSP and the volumetric visualization of the breast tissue in DBT. Our results suggest that novel approaches, different than those conventionally used in projection mammography, need to be investigated in order to develop DBT dense tissue segmentation algorithms for estimating volumetric breast density.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Despina Kontos, Rachelle Berger, Predrag R. Bakic, and Andrew D. A. Maidment "Breast tissue classification in digital breast tomosynthesis images using texture features: a feasibility study", Proc. SPIE 7260, Medical Imaging 2009: Computer-Aided Diagnosis, 726024 (3 March 2009); https://doi.org/10.1117/12.813812
PROCEEDINGS
10 PAGES


SHARE
Advertisement
Advertisement
Back to Top