13 March 2009 Tumor correlated CT: a new paradigm for motion compensated CT for image-guided therapy
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Abstract
Respiratory motion has significant effects on abdominal and lung tumor position, and incorporation of this uncertainty increases volumes for focal cancer treatments. Respiratory correlated CT, obtained by oversampling images throughout the respiratory cycle based on an external surrogate, is increasingly being used for radiation therapy planning. Respiratory correlated CT is dependant on a fixed relationship between the external surrogate and the tumor, which may change based on weight loss, breathing pattern changes or non-respiratory motion. Moreover, the process decouples localization of the tumor (which is the goal of tumor directed therapy) with respiratory motion management. Recently, implantable passive transponders (Calypso Medical Technologies) have been developed which can be tracked via an external electromagnetic array in real-time and without ionizing radiation. We aimed to integrate wireless electromagnetic tracking with multislice CT, and create volumetric datasets that are correlated to tumor position, as opposed to an external surrogate. We call this process 'tumor correlated CT' (TCCT). Use of these images for treatment planning will allow localization of the tumor to predict the position of other organs during treatment delivery. We show the preliminary work in the integration of electromagnetic tracking and CT imaging.
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Parag J. Parikh, Parag J. Parikh, Kristen M. Lechleiter, Kristen M. Lechleiter, Kathleen L. Malinowski, Kathleen L. Malinowski, Ryan L. Smith, Ryan L. Smith, Jie Wen, Jie Wen, Steve Dimmer, Steve Dimmer, } "Tumor correlated CT: a new paradigm for motion compensated CT for image-guided therapy", Proc. SPIE 7261, Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, 726121 (13 March 2009); doi: 10.1117/12.813535; https://doi.org/10.1117/12.813535
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