30 December 2008 Rapid prototyping of multi-level polydimethylsiloxane-based microfluidic devices
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There has been considerable progress in the development of micro-fabricated systems for the field of chemical and biological sciences. Much development has been driven by the need of miniaturized systems that allow cost-effective and rapid processing of samples at the point of need. In this work, we investigate the application practicality of Objet Eden500VTMPolyjet as a rapid and economical tool for multi-level microfluidic device rapid prototyping. The Polyjet is a commercial system that utilizes ink-jet technology to print 3-dimensional structures with photopolymer materials. The reproducing capability of the Polyjet system in term of lateral and vertical resolutions, aspect ratio and smoothness of fabricated structures are investigated. In addition, the capability of the Polyjet is demonstrated by fabricating three different devices including: 1) multi-level microfluidic chip for two-step gene synthesis, 2) a fluidic component for micro/macro fluidic interfacing, and 3) PDMS-based microlens.
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Wai Chye Cheong, Wai Chye Cheong, Yoke Kong Kuan, Yoke Kong Kuan, Mo-Huang Li, Mo-Huang Li, Jackie Y. Ying, Jackie Y. Ying, } "Rapid prototyping of multi-level polydimethylsiloxane-based microfluidic devices", Proc. SPIE 7269, Micro- and Nanotechnology: Materials, Processes, Packaging, and Systems IV, 72690B (30 December 2008); doi: 10.1117/12.810440; https://doi.org/10.1117/12.810440

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