6 March 2009 Optical model for port-wine stain skin and its Monte Carlo simulation
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Laser irradiation is the most acceptable therapy for PWS patient at present time. Its efficacy is highly dependent on the energy deposition rules in skin. To achieve optimal PWS treatment parameters a better understanding of light propagation in PWS skin is indispensable. Traditional Monte Carlo simulations using simple geometries such as planar layer tissue model can not provide energy deposition in the skin with enlarged blood vessels. In this paper the structure of normal skin and the pathological character of PWS skin was analyzed in detail and the true structure were simplified into a hybrid layered mathematical model to character two most important aspects of PWS skin: layered structure and overabundant dermal vessels. The basic laser-tissue interaction mechanisms in skin were investigated and the optical parameters of PWS skin tissue at the therapeutic wavelength. Monte Carlo (MC) based techniques were choused to calculate the energy deposition in the skin. Results can be used in choosing optical dosage. Further simulations can be used to predict optimal laser parameters to achieve high-efficacy laser treatment of PWS.
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Lanqing Xu, Lanqing Xu, Zhengying Xiao, Zhengying Xiao, Rong Chen, Rong Chen, Ying Wang, Ying Wang, } "Optical model for port-wine stain skin and its Monte Carlo simulation", Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 728007 (6 March 2009); doi: 10.1117/12.820778; https://doi.org/10.1117/12.820778

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