Design of a portable noninvasive photoacoustic glucose monitoring system integrated laser diode excitation with annular array detection

Lvming Zeng; Guodong Liu; Diwu Yang; Zhong Ren; Zhen Huang

doi:10.1117/12.822563

6 March 2009 Design of a portable noninvasive photoacoustic glucose monitoring system integrated laser diode excitation with annular array detection

Lvming Zeng, Guodong Liu, Diwu Yang, Zhong Ren, Zhen Huang

Author Affiliations +

Proceedings Volume 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine; 72802F (2009) https://doi.org/10.1117/12.822563
Event: Photonics and Optoelectronics Meetings, 2008, Wuhan, China

Abstract

A near-infrared photoacoustic glucose monitoring system, which is integrated dual-wavelength pulsed laser diode excitation with eight-element planar annular array detection technique, is designed and fabricated during this study. It has the characteristics of nonivasive, inexpensive, portable, accurate location, and high signal-to-noise ratio. In the system, the exciting source is based on two laser diodes with wavelengths of 905 nm and 1550 nm, respectively, with optical pulse energy of 20 μJ and 6 μJ. The laser beam is optically focused and jointly projected to a confocal point with a diameter of 0.7 mm approximately. A 7.5 MHz 8-element annular array transducer with a hollow structure is machined to capture photoacoustic signal in backward mode. The captured signals excitated from blood glucose are processed with a synthetic focusing algorithm to obtain high signal-to-noise ratio and accurate location over a range of axial detection depth. The custom-made transducer with equal area elements is coaxially collimated with the laser source to improve the photoacoustic excite/receive efficiency. In the paper, we introduce the photoacoustic theory, receive/process technique, and design method of the portable noninvasive photoacoustic glucose monitoring system, which can potentially be developed as a powerful diagnosis and treatment tool for diabetes mellitus.

Citation Download Citation

Lvming Zeng, Guodong Liu, Diwu Yang, Zhong Ren, and Zhen Huang "Design of a portable noninvasive photoacoustic glucose monitoring system integrated laser diode excitation with annular array detection", Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 72802F (6 March 2009); https://doi.org/10.1117/12.822563

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