6 March 2009 Theoretical analysis of x-ray CT phase-contrast imaging
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Recently phase contrast imaging has attracted much attention. An obvious advantage of using X-rays for imaging the internal structure of relatively thick samples lies in its high degree of penetration of solid objects. However, often leads to poor image contrast for soft tissue. Phase contrast imaging can be very useful in such situation, as the phase of the transmitted beam may often be more sensitive indicator of density of sample than convention contrast. On the other hand, Computed Tomography is the best technology in the aspect of X-rays detection. Using the technology, the detected object can be imaged to three-dimensional image, so as to observe the inner structure of object, and be convenient to the disease examination. If the phase contrast imaging can be used to the technology of Computed Tomography, the high resolution image can be gained. The technology will become the development orientation of medical image. The aim of this article was to apply the theory of X-rays phase contrast imaging to the traditional X-CT technique. For this purpose, the formula deduced from the imaging theory with parallel monochromatic X-rays illuminating the object based on the Fresnel-Kircohhof theory had been completed and a formula similar to that of the traditional X-CT reconstruction had been gained, which was Radon transform formula. At last, X-rays reconstruction simulation had been carried out according to the formula, and proved that the method could be used in clinical medical imaging. The method discussed in this paper had a very bright prospect for application.
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Sheng Feng, Sheng Feng, Song Liu, Song Liu, Xuelong Zhang, Xuelong Zhang, "Theoretical analysis of x-ray CT phase-contrast imaging", Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 72802K (6 March 2009); doi: 10.1117/12.821569; https://doi.org/10.1117/12.821569

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