Characterization for organic ion-sensitive field effect transistor response for measurement of physiological potassium ion-concentration measurement

Pratysh Rai; Soyoun Jung; Taeksoo Ji; Vijay K. Varadan

doi:10.1117/12.821555

31 March 2009 Characterization for organic ion-sensitive field effect transistor response for measurement of physiological potassium ion-concentration measurement

Pratysh Rai, Soyoun Jung, Taeksoo Ji, Vijay K. Varadan

Author Affiliations +

Proceedings Volume 7291, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009; 72910H (2009) https://doi.org/10.1117/12.821555
Event: SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, 2009, San Diego, California, United States

Abstract

Potassium ion monitoring, in human body, is important for diagnostic and therapeutic purposes. The dynamic response of potassium selective ISFET sensors is instrumental in formulating calibration schema and signal compensations to correct systematic errors. In the research reported here, response characteristics of potassium selective ISFETs were studied. The range of detection was set between 1mM and 25mM to cover all the physiological potassium concentrations. The signals were obtained from an array of sensors, with different aspect ratios, by varying potassium ion concentrations in a time dependent fashion. Normalization of the drain current was used to compensation for variance in order of magnitude observed in different sensors. Sensor response time and linear response range were analyzed, in relation to difference in aspect ratios. Probable modifications in calibration scheme and compensation technique, subjective to the findings, have been suggested.

Citation Download Citation

Pratysh Rai, Soyoun Jung, Taeksoo Ji, and Vijay K. Varadan "Characterization for organic ion-sensitive field effect transistor response for measurement of physiological potassium ion-concentration measurement", Proc. SPIE 7291, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009, 72910H (31 March 2009); https://doi.org/10.1117/12.821555

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