Emergency Diagnostics, Homeland Security, Epidemiological Preparedness and the high cost of the Health
Care Systems have increased demand for affordable and mobile point of care (POC) devices with highest
sensitivity, specificity and rapid time to result. We have developed pocket and brief case sized systems for
point of care and field based tests based on fluorescence read-out. The core consists of battery operated, 90
gram electro-optical units with optional wireless data transfer, which have been optimized to achieve highest
accuracy and sensitivity combined with simplicity of use. The robust systems have been applied to molecular
diagnostics such as DNA based testing, immunodiagnostics as well as environmental monitoring and
agricultural testing. Starting with the current bottlenecks of in-vitro diagnostics testing and a brief market
overview, we will show commercially available portable test systems for molecular diagnostics and how we
solve the current bottlenecks. We will further show battery operated handheld prototypes for DNA testing.
ESE's handheld and portable testing platforms have been shown to provide sensitive, accurate, and specific
results, as well as rapid turnaround. The stand-alone devices demonstrate operational and physical robustness,
and they can be manufactured to be affordable.