8 July 2009 The implementation of an isotope-edited internal standard for quantification of lowest drug concentrations using surface enhanced Raman spectroscopy (SERS) in a lab on a chip device
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Proceedings Volume 7368, Clinical and Biomedical Spectroscopy; 73680R (2009); doi: 10.1117/12.831619
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany
Abstract
The application of surface enhanced Raman spectroscopy in combination with a microfluidic device and an isotopeedited internal standard seems to be a promising way for a new approach for quantitative SERS measurements. An innovative lab on a chip system offers the possibility for reproducible, quantitative online SERS measurements based on the application of isotope labelled internal standards and liquid/liquid segmented flow based flow-through Raman detection. Errors caused by the used method can be compensated by using an internal standard.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Anne März, Petra Rösch, Thomas Henkel, Jürgen Popp, "The implementation of an isotope-edited internal standard for quantification of lowest drug concentrations using surface enhanced Raman spectroscopy (SERS) in a lab on a chip device", Proc. SPIE 7368, Clinical and Biomedical Spectroscopy, 73680R (8 July 2009); doi: 10.1117/12.831619; https://doi.org/10.1117/12.831619
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KEYWORDS
Surface enhanced Raman spectroscopy

Raman spectroscopy

Microfluidics

Silver

Lab on a chip

Raman scattering

Molecules

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