7 July 2009 Sleep apnea termination decreases cerebral blood volume: a near-infrared spectroscopy case study
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Abstract
Medical near-infrared spectroscopy (NIRS) can be used to estimate cerebral haemodynamic changes non-invasively. Sleep apnea is a common sleep disorder where repetitive pauses in breathing decrease the quality of sleep and exposes the individual to various health problems. We have measured oxygenated and deoxygenated haemoglobin concentration changes during apneic events in sleep from the forehead of one subject using NIRS and used principal component analysis to extract extracerebral and cortical haemodynamic changes from NIRS signals. Comparison of NIRS signals with EEG, bioimpedance, and pulse oximetry data suggests that termination of apnea leads to decreases in cerebral blood volume and flow that may be related to neurological arousal via neurovascular coupling.
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Jaakko Virtanen, Tommi Noponen, Tapani Salmi, Jussi Toppila, Pekka Meriläinen, "Sleep apnea termination decreases cerebral blood volume: a near-infrared spectroscopy case study", Proc. SPIE 7368, Clinical and Biomedical Spectroscopy, 73682D (7 July 2009); doi: 10.1117/12.831587; https://doi.org/10.1117/12.831587
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