Structured illumination and time gated detection for diffuse optical imaging

Cosimo D'Andrea; Andrea Bassi; Gianluca Valentini; Rinaldo Cubeddu; Simon Arridge

doi:10.1117/12.831701

9 July 2009 Structured illumination and time gated detection for diffuse optical imaging

Cosimo D'Andrea, Andrea Bassi, Gianluca Valentini, Rinaldo Cubeddu, Simon Arridge

Proceedings Volume 7369, Diffuse Optical Imaging II; 73690Q (2009) https://doi.org/10.1117/12.831701
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany

Abstract

Temporal propagation of sinusoidally modulated light in in-homogeneous diffusive samples is investigated experimentally and by finite element simulations, showing that the amplitude and the phase of the sinusoid are affected by the presence of inclusions. Enhancement of imaging resolution with high spatial frequencies and early time-gating is shown. Detection of the phase of the modulated light is proposed as a new method for the accurate localization of tissue in-homogeneities. A fast 3-dimensional reconstruction based on the detection of spatially modulated light at a limited number of spatial frequencies is discussed.

Citation Download Citation

Cosimo D'Andrea, Andrea Bassi, Gianluca Valentini, Rinaldo Cubeddu, and Simon Arridge "Structured illumination and time gated detection for diffuse optical imaging", Proc. SPIE 7369, Diffuse Optical Imaging II, 73690Q (9 July 2009); https://doi.org/10.1117/12.831701

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