A new deconvolution technique for time-domain signals in diffuse optical tomography without a priori information

Geoffroy Bodi; Yves Bérubé-Lauzière

doi:10.1117/12.831687

9 July 2009 A new deconvolution technique for time-domain signals in diffuse optical tomography without a priori information

Geoffroy Bodi, Yves Bérubé-Lauzière

Author Affiliations +

Proceedings Volume 7369, Diffuse Optical Imaging II; 736914 (2009) https://doi.org/10.1117/12.831687
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany

Abstract

The present work will serve in a diffuse optical tomography (DOT) scanner that we are developing for small animal non-contact molecular imaging. We present a new method for deconvoluting time-domain signals for use in DOT. Time-domain signals represents reemitted light intensity as a function of time when the medium is excited by ultra-short laser pulses. Actually, each signal equals the convolution between the light propagation in the medium and the impulse response of the detection system, so-called the instrument response function (IRF). Moreover, Poisson noise present in the system has to be considered. Time-domain signals directly depend on the optical properties of a medium and so contain additional information (compared to continuous-wave signals) that should be exploited in reconstruction algorithms. As an advantage, our deconvolution method does not use a priori information about the signal. It is important to remove the IRF and noise from measured signals in order to keep only the true signal, which has a direct link to medium properties.

Citation Download Citation

Geoffroy Bodi and Yves Bérubé-Lauzière "A new deconvolution technique for time-domain signals in diffuse optical tomography without a priori information", Proc. SPIE 7369, Diffuse Optical Imaging II, 736914 (9 July 2009); https://doi.org/10.1117/12.831687

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