1 July 2009 Dual-modality molecular imaging for small animals using fluorescence and x-ray computed tomography
Author Affiliations +
Proceedings Volume 7370, Molecular Imaging II; 73700G (2009); doi: 10.1117/12.831719
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany
We demonstrate the feasibility of using a dual-modality fluorescence and x-ray computed tomography (CT) system for quantitative molecular imaging with phantom studies. A CCD based non-contact FT system, which can take measurements from multiple views was built. High-resolution X-Ray CT was used to obtain structural information from the phantom. A 3.6 mm diameter fluorescence inclusion was deeply embedded in the heterogeneous optical background. The results demonstrated that the fluorophore concentration can only be obtained accurately when guided by the a priori information provided by the x-ray CT.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yuting Lin, William C. Barber, Jan S. Iwanczyk, Einar Nygard, Nail Malakov, Neal E. Hartsough, Thulasi Gandhi, Werner W. Roeck, Orhan Nalcioglu, Gultekin Gulsen, "Dual-modality molecular imaging for small animals using fluorescence and x-ray computed tomography", Proc. SPIE 7370, Molecular Imaging II, 73700G (1 July 2009); doi: 10.1117/12.831719; https://doi.org/10.1117/12.831719

Fourier transforms


X-ray computed tomography


Molecular imaging


Inverse optics

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