9 July 2009 Fiber bundle based fluorescence tomography system for human breast imaging
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Abstract
Fluorescence diffuse optical tomography (FT) is a promising molecular imaging technique that can spatially resolve both fluorophore concentration and lifetime parameters. In this phantom study, we built a photo-multiplier tube (PMT) based single detection system that uses fiber bundles to collect light. Measurements were acquired both with a 1 mm diameter single fiber and a 6 mm diameter fiber bundle using the very same detection unit for comparison purposes. We demonstratethat the fluorescence concentration and lifetime can be well recovered for 6 mm diameter objects deeply embedded in an 80 mm diameter breast-sized phantom when the fiber bundle is utilized.
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Yuting Lin, Orhan Nalcioglu, Gultekin Gulsen, "Fiber bundle based fluorescence tomography system for human breast imaging", Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 737108 (9 July 2009); doi: 10.1117/12.831770; https://doi.org/10.1117/12.831770
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