9 July 2009 Enhancement of cancerous/normal tissue contrast via combined white light and fluorescence image processing: initial investigation ex vivo
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Abstract
In the current study we try to optimise the cancerous/normal tissue contrast perception using white light and autofluorescence image processing. We deconvolved the RGB channels of both white light and autofluorescence images pixel by pixel and pointed out the best contrast enhancement technique, manipulating each channel seperately. By using false-color mapping according to a particular Look-Up Table, the borders between normal and cancerous area of the tissue are better delineated. Cancer tissue identification was confirmed by the histological examination that followed our investigation.
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Angelos A. Kalitzeos, Angelos A. Kalitzeos, Azhar Zam, Azhar Zam, Florian Stelzle, Florian Stelzle, Eckhart G. Hahn, Eckhart G. Hahn, Martin Raithel, Martin Raithel, Alexandre Douplik, Alexandre Douplik, } "Enhancement of cancerous/normal tissue contrast via combined white light and fluorescence image processing: initial investigation ex vivo", Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73710N (9 July 2009); doi: 10.1117/12.831771; https://doi.org/10.1117/12.831771
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