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9 July 2009 Monitoring of epithelium capillary density
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Abstract
Monitoring the epithelium vessel capillary density pattern is critically important for preventing rapidly developing life threatening syndromes such as shock or systemic organ failures. The objective of this study is real time monitoring of epithelium vessel density pattern. The fiber sensor will be based on spatially resolved diffuse reflectance spectra. The parameters comprising period and depth of capillary spatial modulation are exploited for shock detection. The preliminary investigations with simulated spectra have shown that the new method can reasonably extracts minor deviations of oxygenation and local volume blood fraction - parameters, directly related to the local vessel density. The original method developed to use these parameters is much less dependent on light scattering in visible range as opposed to the most of the currently used methods.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Rajesh Kanawade, Gennadiy Saiko, and Alexandre Douplik "Monitoring of epithelium capillary density", Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73711L (9 July 2009); https://doi.org/10.1117/12.831725
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