Evaluation of microfluidic channels with optical coherence tomography

J. Czajkowski; T. Prykäri; E. Alarousu; J. Lauri; R. Myllylä

doi:10.1117/12.871445

24 November 2010 Evaluation of microfluidic channels with optical coherence tomography

J. Czajkowski, T. Prykäri, E. Alarousu, J. Lauri, R. Myllylä

Proceedings Volume 7376, Laser Applications in Life Sciences; 737617 (2010) https://doi.org/10.1117/12.871445
Event: Laser Applications in Life Sciences 2010, 2010, Oulu, Finland

Abstract

Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.

Citation Download Citation

J. Czajkowski, T. Prykäri, E. Alarousu, J. Lauri, and R. Myllylä "Evaluation of microfluidic channels with optical coherence tomography", Proc. SPIE 7376, Laser Applications in Life Sciences, 737617 (24 November 2010); https://doi.org/10.1117/12.871445

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available