13 July 2009 Photodynamic therapy of cervical intraepithelial neoplasia using hexaminolevulinate and methylaminolevulinate
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Proceedings Volume 7380, Photodynamic Therapy: Back to the Future; 738031 (2009); doi: 10.1117/12.824462
Event: 12th World Congress of the International Photodynamic Association, 2009, Seattle, Washington, United States
Abstract
Cervical intraepithelial neoplasia (CIN) is the precursor of invasive cervical cancer. Previous studies indicated that photodynamic therapy (PDT) represents an effective treatment modality in CIN. In 28 patients with CIN 1 - 3, 1 - 2 cycles of PDT were conducted using hexaminolevulinate (HAL) or methylaminolevulinate (MAL) and a special light delivery system. After 6 months, biopsies were obtained to assess response. The overall response rate for complete or partial response was 65%. Photodynamic therapy using new ALA esters is effective and may offer unique advantages in the therapy of CIN.
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Philipp Soergel, Ismini Staboulidou, Herrmann Hertel, Cordula Schippert, Peter Hillemanns, "Photodynamic therapy of cervical intraepithelial neoplasia using hexaminolevulinate and methylaminolevulinate", Proc. SPIE 7380, Photodynamic Therapy: Back to the Future, 738031 (13 July 2009); doi: 10.1117/12.824462; https://doi.org/10.1117/12.824462
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KEYWORDS
Photodynamic therapy

Luminescence

Tissues

Cell biology

Cervical cancer

Forensic DNA analysis

Statistical analysis

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