Recently, low-level laser therapy (LLLT) has been reported to have a photobiomodulation effect on bio-tissues. Our aim
was to evaluate the effect of low level GaAlAs laser on bone regeneration around bone defect sites created surgically in
rabbit femur. Thirty rabbits were randomly divided into an experimental and a control groups. A GaAlAs semiconductor
diode laser was applied in the experimental group( λ = 808nm, P =75mW, (symbol) =0.4mm,t=5min,
ρE=28J/cm2)immediately after surgery once a day for 3 consecutive days with no irradiation in the control group.
Rabbits were sacrificed on the 7th, 14th, 21th days after surgery (DAS) and femur samples were prepared for bone
histomorphometry analysis. The results showed that the bone volume, the osteoid volume, osteoblast surface and the
mineral apposition rate in the laser group were higher statistically (P<0.05) than those indices in the control group at
different periods. These data revealed that LLLT can enhance bone regeneration. LLLT seems to have a clinical
application in promoting bone healing around implant in the future.