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21 August 2009 Functional modular contact lens
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Proceedings Volume 7397, Biosensing II; 73970K (2009) https://doi.org/10.1117/12.827720
Event: SPIE NanoScience + Engineering, 2009, San Diego, California, United States
Abstract
Tear fluid offers a potential route for non-invasive sensing of physiological parameters. Utilization of this potential depends on the ability to manufacture sensors that can be placed on the surface of the eye. A contact lens makes a natural platform for such sensors, but contact lens polymers present a challenge for sensor fabrication. This paper describes a microfabrication process for constructing sensors that can be integrated into the structure of a functional contact lens in the future. To demonstrate the capabilities of the process, an amperometric glucose sensor was fabricated on a polymer substrate. The sensor consists of platinum working and counter electrodes, as well as a region of indium-tin oxide (ITO) for glucose oxidase immobilization. An external silver-silver chloride electrode was used as the reference electrode during the characterization experiments. Sensor operation was validated by hydrogen peroxide measurements in the 10- 20 μM range and glucose measurements in the 0.125-20 mM range.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Angela J. Shum, Melissa Cowan, Ilkka Lähdesmäki, Andrew Lingley, Brian Otis, and Babak A. Parviz "Functional modular contact lens", Proc. SPIE 7397, Biosensing II, 73970K (21 August 2009); https://doi.org/10.1117/12.827720
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