Enhanced sensitivity by optimizing metal thicknesses in intensity-interrogation surface plasmon resonance biosensors

Chung-Tien Li; Ta-Jen Yen

doi:10.1117/12.826826

21 August 2009 Enhanced sensitivity by optimizing metal thicknesses in intensity-interrogation surface plasmon resonance biosensors

Chung-Tien Li, Ta-Jen Yen

Author Affiliations +

Proceedings Volume 7397, Biosensing II; 739716 (2009) https://doi.org/10.1117/12.826826
Event: SPIE NanoScience + Engineering, 2009, San Diego, California, United States

Abstract

Intensity interrogation of SPR biosensor owns high sensitivity, and is generally used as SPR microscopy due to the optical intensity variation. Therefore, it is substantial to improve its sensitivity to have a better sensing ability and image quality. In this paper, we discussed numerically and experimentally the influence of sensitivity by metal thickness, and provide a design rule of manifesting optimized thickness to maximize sensitivity in intensity interrogation.

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Chung-Tien Li and Ta-Jen Yen "Enhanced sensitivity by optimizing metal thicknesses in intensity-interrogation surface plasmon resonance biosensors", Proc. SPIE 7397, Biosensing II, 739716 (21 August 2009); https://doi.org/10.1117/12.826826

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