25 November 2009 Progress of OCT and its applications
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Abstract
Optical coherence tomography (OCT) is the cross-sectional imaging of biological tissue based on the low-coherence interferometry, where the image resolution is around 10 ìm with the imaging depth of 1 to 2 mm. Since its first demonstration, OCT has been developed intensively for clinical diagnoses of ophthalmology and arteriosclerosis. Beside the clinical applications, OCT is used for analysis of physiological functions underneath the human skin surface. Recently, we proposed and demonstrated the dynamic OCT for in vivo observation of physiological functions of small organs underneath the skin surface. In the dynamic OCT, tomographic images are obtained time-sequentially for tracking of the dynamics of eccrin sweat glands and peripheral vessels. In the last three years, the dynamic skin physiology has been analyzed using both time-domain (TD) OCT and swept source (SS) OCT. In this paper, we present progress of OCT as well as the dynamic analysis of mental sweating and pulsation of a small artery in synchronization with the heartbeat using SS-OCT.
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Masato Ohmi, Masato Ohmi, Masamitsu Haruna, Masamitsu Haruna, } "Progress of OCT and its applications", Proc. SPIE 7506, 2009 International Conference on Optical Instruments and Technology: Optical Systems and Modern Optoelectronic Instruments, 750609 (25 November 2009); doi: 10.1117/12.837566; https://doi.org/10.1117/12.837566
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