28 October 2009 A meta-analysis of aneurysm formation in laser assisted vascular anastomosis (LAVA)
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Laser assisted vascular anastomosis (LAVA) is looked as a particularly promising non-suture method in future. However, aneurysm formation is one of the main reasons delay the clinical application of LAVA. Some scientists investigated the incidence of aneurysms in animal model. To systematically analyze the literature on reported incidence of aneurysm formation in LAVA therapy, we performed a meta-analysis comparing LAVA with conventional suture anastomosis (CSA) in animal model. Data were systematically retrieved and selected from PUBMED. In total, 23 studies were retrieved. 18 studies were excluded, and 5 studies involving 647 animals were included. Analysis suggested no statistically significant difference between LAVA and CSA (OR 1.24, 95%CI 0.66-2.32, P=0.51). Result of meta analysis shows that the technology of LAVA is very close to clinical application.
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Chen Chen, Chen Chen, Fei Peng, Fei Peng, Dahai Xu, Dahai Xu, Qinghua Cheng, Qinghua Cheng, "A meta-analysis of aneurysm formation in laser assisted vascular anastomosis (LAVA)", Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 751903 (28 October 2009); doi: 10.1117/12.841885; https://doi.org/10.1117/12.841885

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