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28 October 2009 Thermoacoustic measurement of the temperature during microwave thermotherapy
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Microwave thermotherapy (MT) has been an important treatment in oncology. The measurement of temperature during microwave thermotherapy is vital to ensure the safety of normal tissues. Thermoacoustic signals induced are temperature dependent. This phenomenon demonstrates that the thermal parameters are closely related to the generation of thermoacoustic pressure. Here we present the studies on pulsed microwave-induced thermoacoustic signals toward temperature monitoring of tissue thermotherapy. A high power pulsed microwave was used as thermoacoustic excitation source and heating source simultaneously, thermoacoustic pressure was captured by a multi-element linear transducer array. Excellent agreement was obtained between the inversion calculation results and the actual measurement temperature. The results suggest that thermoacoustic signals can be used to monitor thermotherapy temperature, and has the potential of reconstruct the temperature distribution by filter back-projection algorithm. This method has a great potential to develop into an integrated system for pulsed microwave thermotherapy and curative effect monitoring.
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Cunguang Lou, Da Xing, and Liming Nie "Thermoacoustic measurement of the temperature during microwave thermotherapy", Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 75191S (28 October 2009);

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