14 April 2010 Ring resonators and micro fluidics: novel design for drug/disease detection
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Proceedings Volume 7522, Fourth International Conference on Experimental Mechanics; 75222M (2010) https://doi.org/10.1117/12.851651
Event: Fourth International Conference on Experimental Mechanics, 2009, Singapore, Singapore
Abstract
MEMS systems are technologically developed from integrated circuit industry to create miniature sensors and actuators. Originally these semiconductor processes and materials were used to build electrical and mechanical systems, but expanded to include biological, optical fluidic magnetic and other systems [12]. Here a novel approach is suggested where in two different fields are integrated via moems, micro fluidics and ring resonators. It is well known at any preliminary stage of disease onset, many physiological changes occur in the body fluids like saliva, blood, urine etc. The drawback till now was that current calibrations are not sensitive enough to detect the minor physiological changes. This is overcome using optical detector techniques [1]. The basic concepts of ring resonators, with slight variations can be used for optical detection of these minute disease markers. A well known fact of ring resonators is that a change in refractive index will trigger a shift in the resonant wavelength [5]. The trigger for the wavelength shift in the case discussed will be the presence of disease agents. To trap the disease agents specific antibody has to be used (e.g. BSA).
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Ganesh Shanbhag, Ganesh Shanbhag, Varsha Vishwanath, Varsha Vishwanath, T. Srinivas, T. Srinivas, } "Ring resonators and micro fluidics: novel design for drug/disease detection", Proc. SPIE 7522, Fourth International Conference on Experimental Mechanics, 75222M (14 April 2010); doi: 10.1117/12.851651; https://doi.org/10.1117/12.851651
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