2 March 2010 A clinical probe for combined Raman spectroscopy-optical coherence tomography (RS-OCT) of the skin cancers
Author Affiliations +
Proceedings Volume 7548, Photonic Therapeutics and Diagnostics VI; 75480L (2010) https://doi.org/10.1117/12.843708
Event: SPIE BiOS, 2010, San Francisco, California, United States
Abstract
Skin cancer is the most commonly occurring cancer, with incidence rates rising annually. Realizing favorable outcomes requires early diagnosis, for which the current standard is biopsy followed by histopathology. This process can be invasive, subjective, time consuming, and costly. Optical techniques, including Optical Coherence Tomography (OCT) and Raman Spectroscopy (RS), have been developed to perform non-invasive characterization of skin lesions, however neither is without limitation. Here, we demonstrate a clinical instrument for morphological and biochemical characterization of skin cancers with combined RS-OCT. The portable instrument utilizes independent RS and OCT system backbones, and is integrated in a common clinical probe. The potential of the probe for cancer diagnosis is demonstrated on malignant and non-malignant lesions.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chetan A. Patil, Chetan A. Patil, Harish Krishnamoorthi, Harish Krishnamoorthi, Darrel L. Ellis, Darrel L. Ellis, Ton G. van Leeuwen, Ton G. van Leeuwen, Anita Mahadevan-Jansen, Anita Mahadevan-Jansen, } "A clinical probe for combined Raman spectroscopy-optical coherence tomography (RS-OCT) of the skin cancers", Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 75480L (2 March 2010); doi: 10.1117/12.843708; https://doi.org/10.1117/12.843708
PROCEEDINGS
6 PAGES


SHARE
Back to Top