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2 March 2010 Optimizing treatment parameters for the vascular malformations using 1064-nm Nd:YAG laser
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Proceedings Volume 7548, Photonic Therapeutics and Diagnostics VI; 75480S (2010)
Event: SPIE BiOS, 2010, San Francisco, California, United States
Near infrared Nd:YAG pulsed laser treatment had been proved to be an efficient method to treat large-sized vascular malformations like leg telangiectasia for deep penetrating depth into skin and uniform light distribution in vessel. However, optimal clinical outcome was achieved by various laser irradiation parameters and the key factor governing the treatment efficacy was still unclear. A mathematical model in combination with Monte Carlo algorithm and finite difference method was developed to estimate the light distribution, temperature profile and thermal damage in epidermis, dermis and vessel during and after 1064 nm pulsed Nd:YAG laser irradiation. Simulation results showed that epidermal protection could be achieved during 1064 nm Nd:YAG pulsed laser irradiation in conjunction with cryogen spray cooling. However, optimal vessel closure and blood coagulation depend on a compromise between laser spot size and pulse duration.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Wei Gong, He Lin, and Shusen Xie "Optimizing treatment parameters for the vascular malformations using 1064-nm Nd:YAG laser", Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 75480S (2 March 2010);

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