2 March 2010 Experimental retinectomy with a 6.1 μm Q-switched Raman-shifted alexandrite laser
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Proceedings Volume 7550, Ophthalmic Technologies XX; 75500X (2010) https://doi.org/10.1117/12.846890
Event: SPIE BiOS, 2010, San Francisco, California, United States
Abstract
Purpose: It is hypothesized that 6.1 μm produced by a portable laser would be useful for incising tissue layers such as performing a retinectomy in detached retina with extensive anterior proliferative vitreoretinopathy. Methods: An alexandrite laser system, which provides a high-intensity Q-switched pulse (780 nm, 50-100 ns duration, 10 Hz), is wavelength-shifted by a two-stage stimulated Raman conversion process into the 6-7 μm range (Light Age, Inc.). Fresh cadaver porcine retinas were lased with 6.1 μm using a 200 μm diameter spot at 0.6 mJ after removal of the vitreous. Specimens were examined grossly and prepared for histological examination. Results: The Raman-shifted alexandrite laser produced a smooth Gaussian profile. A narrow spectrum was produced at 6.1 μm. A full-thickness retinal incision with minimal thermal damage was obtained at a low energy level of 0.6 mJ in the retinas. However, the depth of the incision did vary from an incomplete incision to a full-thickness incision involving the underlying choroidal layer in attached retinas. Conclusions: The 6.1 μm mid-infrared energy produced by a portable laser is capable of incising detached retinas with minimal thermal damage.
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Karen M. Joos, Ratna Prasad, John Kozub, Borislav Ivanov, Anita Agarwal, Jin H. Shen, "Experimental retinectomy with a 6.1 μm Q-switched Raman-shifted alexandrite laser", Proc. SPIE 7550, Ophthalmic Technologies XX, 75500X (2 March 2010); doi: 10.1117/12.846890; https://doi.org/10.1117/12.846890
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