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2 March 2010 In vivo, dual-modality imaging of mouse eyes: optical coherence tomography and photoacoustic microscopy within a single instrument
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Proceedings Volume 7550, Ophthalmic Technologies XX; 75501Q (2010) https://doi.org/10.1117/12.843041
Event: SPIE BiOS, 2010, San Francisco, California, United States
Abstract
Optical-resolution photoacoustic microscopy (OR-PAM) provides superb optical absorption contrast for red blood cells (RBCs), which makes it ideal for in vivo microvasculature imaging. In comparison, optical coherence tomography (OCT), widely used for tissue microstructure imaging, provides high optical scattering contrast. The two contrast mechanisms are highly complementary. In this work, we combined OR-PAM and OCT into a single, dual-modality imaging instrument for in vivo mouse eye imaging. We demonstrated in vivo dual-modality imaging of the anterior segment of mouse eyes with laser pulse energy within the ANSI laser safety standard.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Bin Rao, Li Li, Konstantin Maslov, and Lihong V. Wang "In vivo, dual-modality imaging of mouse eyes: optical coherence tomography and photoacoustic microscopy within a single instrument", Proc. SPIE 7550, Ophthalmic Technologies XX, 75501Q (2 March 2010); doi: 10.1117/12.843041; https://doi.org/10.1117/12.843041
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