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2 March 2010 In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions
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Abstract
For the fist time worldwide we report high amplitude NIR-Luminescence signals, measured in pig skin. The measurements are achieved with a recently developed setup that was shown to provide superior performance for 1O2- luminescence detection in vitro. This setup has been adapted to allow now the detection of singlet oxygen signals in vivo. Pig ears were used for first measurements as a widely accepted in vivo model for human skin.
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Jan Schlothauer, Beate Röder, Steffen Hackbarth, and Jürgen Lademann "In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions", Proc. SPIE 7551, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIX, 755106 (2 March 2010); https://doi.org/10.1117/12.839851
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