17 February 2010 Microcavities in photonic crystal waveguides for biosensor applications
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In this study, resonant microcavities in photonic crystal (PhC) waveguides are investigated for biosensing applications. The device architecture consists of a PhC waveguide with a defect line for guiding the transmission of light. Resonant microcavities created by changing the radius of a hole adjacent to the defect line are coupled to the PhC waveguide. Detection is based on shifts in the resonance wavelength observed in the transmission spectra. The PhC waveguide device is fabricated on silicon-on-insulator (SOI) wafers using electron beam lithography and reactive-ion etching (RIE). Receptor molecules are attached to the defects in the device by standard amino-silane and glutaraldehyde crosslinking chemistry. Preliminary results demonstrate successful detection of human IgG molecules as the target at large concentration levels of 500 μg/ml. Such PhC waveguide devices are advantageous for medical diagnostics and biosecurity applications as they allow rapid, label-free, and sensitive detection of multiple analytes in a single platform.
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Sudeshna Pal, Sudeshna Pal, Elisa Guillermain, Elisa Guillermain, Rashmi Sriram, Rashmi Sriram, Benjamin Miller, Benjamin Miller, Philippe M. Fauchet, Philippe M. Fauchet, } "Microcavities in photonic crystal waveguides for biosensor applications", Proc. SPIE 7553, Frontiers in Pathogen Detection: From Nanosensors to Systems, 755304 (17 February 2010); doi: 10.1117/12.848237; https://doi.org/10.1117/12.848237

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