18 February 2010 Optical fiber guided needle insertion to localize epidural space in porcine
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A novel optical method of guiding epidural catheter insertion is introduced due to high failure rate of traditional technique for epidural blocks. Experiments of ex-vivo and in-vivo in porcine were performed. In the ex-vivo study the optically reflective spectra of identified porcine tissues were obtained. By which wavelengths of 650 nm and 532 nm were selected to differentiate epidural space and ligamentum flavum. Then the typical stylet of an insertion needle set was replaced by a specially designed hollow stylet which contained optical fibers served for tissue illumination and receiving reflected light from tissue in the in-vivo experiment in pigs. The data was promising with mean magnitudes for 650 nm and 532 nm and their ratio at epidural space and ligamentum flavum were 3.565+/-0.194, 2.542+/-0.145, 0.958+/-0.172 and 3.842+/-0.191, 2.563+/-0.131, 1.228+/-0.244 respectively. Paired t test showed that significant differences occurred between epidural spaces and ligamentum flavum in both 650nm (p<0.001), 532nm (p=0.014) and their ratio (p <0.001). Two-way ANOVA for reflective lights of 650 and 532 nm indicates no significant difference at the different puncture sites for ligamentum flavum and epidural space (all p>0.05).
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Yin Chang, Yin Chang, Chien Kun Ting, Chien Kun Ting, Mei-Yung Tsou, Mei-Yung Tsou, Pin-Tarng Chen, Pin-Tarng Chen, Kwok-Hon Chan, Kwok-Hon Chan, } "Optical fiber guided needle insertion to localize epidural space in porcine", Proc. SPIE 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII, 755505 (18 February 2010); doi: 10.1117/12.841200; https://doi.org/10.1117/12.841200

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