Improving the success of lumpectomies would reduce the number of procedures, cost, and morbidity. A light
source could be placed in a lesion to assist in finding and removing the lesion. A quantitive measurement of the
distance between such a light source and a detector would further aid in the procedure by providing surgeons
with easy to use intra-operative guidance to the lesion.
Two methods, continuous wave and frequency domain, of accomplishing this measurement were compared.
Within one radio frequency experimental system, the amplitude at 15MHz was taken to represent the continuous
wave signal and the phase at 100MHz was taken to represent the frequency domain signal. For the continuous
wave method, data at source-detector separation distances of 20, 30 & 50mm were used to predict other distances
of 10, 20, 30, 40, & 50 mm. Data at source-detector separation distances of 20 & 40mm was used to predict
distances for the frequency domain method.
When the difference between the predicted distance and the actual distance was compared to zero the continuous
wave method was significantly different (student's t-test, p = 0.03) while the frequency domain method was
not statistically different from zero (student'st-test, p > 0.05). The frequency domain method was more accurate
at predicting the source-detector separation distance between 10 & 50 mm. This frequency domain method of
measuring distance may be useful in locating and removing lesions during lumpectomy procedures.