Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) imaging system

Jiechen Yin; Hao-Chung Yang; Xiang Li; Qifa Zhou; Changhong Hu; Jun Zhang; K. Kirk Shung; Zhongping Chen

doi:10.1117/12.841375

23 February 2010 Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) imaging system

Jiechen Yin, Hao-Chung Yang, Xiang Li, Qifa Zhou, Changhong Hu, Jun Zhang, K. Kirk Shung, Zhongping Chen

Proceedings Volume 7557, Multimodal Biomedical Imaging V; 75570D (2010) https://doi.org/10.1117/12.841375
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Optical coherence tomography (OCT) and intravascular ultrasound (IVUS) are considered two complementary imaging techniques in the detection and diagnosis of atherosclerosis. OCT permits visualization of micron-scale features of atherosclerosis plaque, and IVUS offers full imaging depth of vessel wall. Under the guidance of IVUS, minimal amount of flushing agent will be needed to obtain OCT imaging of the interested area. We report on a dual-modality optical coherence tomography (OCT) - ultrasound (US) system for intravascular imaging. To the best of our knowledge, we have developed the first integrated OCT-US probe that combines OCT optical components with an ultrasound transducer. The OCT optical components mainly consist of a single mode fiber, a gradient index (GRIN) lens for light beam focusing, and a right-angled prism for reflecting light into biological tissue. A 40MHz PZT-5H side-viewing ultrasound transducer was fabricated to obtain the ultrasound image. These components were integrated into a single probe, enabling both OCT and ultrasound imaging at the same time. In vitro OCT and ultrasound images of a rabbit aorta were obtained using this dual-modality imaging system. This study demonstrates the feasibility of an OCT-US system for intravascular imaging which is expected to have a prominent impact on early detection and characterization of atherosclerosis.

Citation Download Citation

Jiechen Yin, Hao-Chung Yang, Xiang Li, Qifa Zhou, Changhong Hu, Jun Zhang, K. Kirk Shung, and Zhongping Chen "Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) imaging system", Proc. SPIE 7557, Multimodal Biomedical Imaging V, 75570D (23 February 2010); https://doi.org/10.1117/12.841375

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Optical coherence tomography

Ultrasonography

Imaging systems

Intravascular ultrasound

Transducers

Optical components

Signal detection

Show All Keywords

Keywords/Phrases

Search In:

Publication Years