25 February 2010 Guided-mode resonance sensor system for early detection of ovarian cancer
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Abstract
A high-accuracy sensor system has been developed that provides near-instantaneous detection of biomarker proteins as indicators of ovarian serous papillary carcinoma. Based upon photonic guided-mode resonance technology, these highresolution sensors employ multiple resonance peaks to rapidly test for relevant proteins in complex biological samples. This label-free sensor approach requires minimal sample processing and has the capability to measure multiple agents simultaneously and in real time. A detection system has been developed and performance characterized. Identification and quantification of protein biomarkers that are up- or downregulated in blood and serum as indicators of ovarian cancer will be presented.
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Debra Wawro, Peter Koulen, Yiwu Ding, Shelby Zimmerman, Robert Magnusson, "Guided-mode resonance sensor system for early detection of ovarian cancer", Proc. SPIE 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics, 75720D (25 February 2010); doi: 10.1117/12.842725; https://doi.org/10.1117/12.842725
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