17 February 2010 Compact and fast read-out for wavelength-encoded biosensors
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Abstract
Many established and recently-introduced optical biosensor concepts rely on the detection of a small wavelength change in response to change of temperature, adhesion of bio-particles, strain, or chemical environment. Special coatings are used to sensitize them to specifically bound molecules (e.g., biomarkers). We describe a compact and fast wavelength monitor that can resolve sub-pm wavelength changes. The unit was demonstrated by reading out a FBG sensor and can resolve wavelength changes as small as 50fm with a bandwidth of more than 100Hz.
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Konrad Bellmann, Konrad Bellmann, Peter Kiesel, Peter Kiesel, Noble Johnson, Noble Johnson, } "Compact and fast read-out for wavelength-encoded biosensors", Proc. SPIE 7593, Microfluidics, BioMEMS, and Medical Microsystems VIII, 75930X (17 February 2010); doi: 10.1117/12.842787; https://doi.org/10.1117/12.842787
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