9 March 2010 Source separation on hyperspectral cube applied to dermatology
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This paper proposes a method of quantification of the components underlying the human skin that are supposed to be responsible for the effective reflectance spectrum of the skin over the visible wavelength. The method is based on independent component analysis assuming that the epidermal melanin and the dermal haemoglobin absorbance spectra are independent of each other. The method extracts the source spectra that correspond to the ideal absorbance spectra of melanin and haemoglobin. The noisy melanin spectrum is fixed using a polynomial fit and the quantifications associated with it are reestimated. The results produce feasible quantifications of each source component in the examined skin patch.
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J. Mitra, J. Mitra, R. Jolivot, R. Jolivot, P. Vabres, P. Vabres, F. S. Marzani, F. S. Marzani, "Source separation on hyperspectral cube applied to dermatology", Proc. SPIE 7624, Medical Imaging 2010: Computer-Aided Diagnosis, 76243I (9 March 2010); doi: 10.1117/12.844044; https://doi.org/10.1117/12.844044

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