23 February 2010 Non-rigid registration for quantification of intestinal peristalsis on dynamic MRI data
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Diseases of the intestinal tract often begin with changes altering the bowel tissue elasticity. Therefore, quantification of bowel motion would be desirable for diagnosis, treatment monitoring and follow-up. Dynamic MRI can capture such changes, but quantification requires non-rigid registration. Towards a computer-assisted quantification for bowel diseases, two innovative methods for detection of bowel motility restrictions have been developed and evaluated. Therefore a coronal 2D+t image will be extracted from a dynamic 3D MRI dataset and registered non-rigidly over multiple time steps. The first method generates a new image from the resulting motion maps by adding the absolute value of the vector for each pixel to the corresponding values in following time steps. The second method calculates the absolute values only from the lateral part of the vectors, skipping the coronal part, and thus removes large distortions due to movements caused by breathing. In this preliminary evaluation both methods will be compared in regard to 5 healthy subjects (volunteers) and 5 patients with proven restrictions in bowel motility. It was shown, that for the first method with respiration a classification of volunteers and patients is only partly possible. However, the second method turns out to be capable of classifying normal and restricted bowel peristalsis. For the second method the mean motion from patients motion maps are about 34.4% lower than that from volunteers motion maps. Therefore, for the first time such a classification is possible.
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Daniel Stein, Daniel Stein, Tobias Heye, Tobias Heye, Hans-Ulrich Kauczor, Hans-Ulrich Kauczor, Hans-Peter Meinzer, Hans-Peter Meinzer, "Non-rigid registration for quantification of intestinal peristalsis on dynamic MRI data", Proc. SPIE 7625, Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, 76251Y (23 February 2010); doi: 10.1117/12.844174; https://doi.org/10.1117/12.844174

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