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23 February 2010 Realistic colon simulation in CT colonography using mesh skinning
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Realistic colon simulations do not exist but would be valuable for CT colonography (CTC) CAD development and validation of new colon image processing algorithms. The human colon is a convoluted tubular structure and very hard to model physically and electronically. In this investigation, we propose a novel approach to generate realistic colon simulation using mesh skinning. The method proceeds as follows. First, a digital phantom of a cylindrical tube is modeled to simulate a straightened colon. Second, haustral folds and teniae coli are added to the cylindrical tube. Third, a centerline equipped with rotation-minimizing frames (RMF) and distention values is computed. Fourth, mesh skinning is applied to warp the tube around the centerline and generate realistic colon simulation. Lastly, colonic polyps in the shape of ellipsoids are also modeled. Results show that the simulated colon highly resembles the real colon. This is the first colon simulation that incorporates most colon characteristics in one model, including curved centerline, variable distention, haustral folds, teniae coli and colonic polyps.
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Jianhua Yao, Ananda S. Chowdhury, and Ronald M. Summers M.D. "Realistic colon simulation in CT colonography using mesh skinning", Proc. SPIE 7625, Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, 76252J (23 February 2010);

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