Liquid lens enabled optical coherence microscope with Gabor fusion

Jannick P. Rolland; Supraja Murali; Panomsak Meemon; William Kuhn; Kevin P. Thompson; Kye-Sung Lee

doi:10.1117/12.871356

9 September 2010 Liquid lens enabled optical coherence microscope with Gabor fusion

Jannick P. Rolland, Supraja Murali, Panomsak Meemon, William Kuhn, Kevin P. Thompson, Kye-Sung Lee

Proceedings Volume 7652, International Optical Design Conference 2010; 76522C (2010) https://doi.org/10.1117/12.871356
Event: International Optical Design Conference 2010, 2010, Jackson Hole, WY, United States

Abstract

A custom optical microscope with an integrated liquid lens to enable an extended depth imaging in biological tissue has been fabricated and shown to provide subcellular resolution using Gabor image fusion in an optical coherence tomography setup. In this paper, we report on the development and assessment path of this technology over the last few years. Specifically, we report on the optical design as well as the MTF prediction and experimental measurements of the new optical microscope head. The microscope head was integrated in a custom optical coherence microscopy setup that is presented. Images of an African frog tadpole, ex vivo human breast excised tissue, and in vivo skin images, acquired with the integrated instrument, are presented.

Citation Download Citation

Jannick P. Rolland, Supraja Murali, Panomsak Meemon, William Kuhn, Kevin P. Thompson, and Kye-Sung Lee "Liquid lens enabled optical coherence microscope with Gabor fusion", Proc. SPIE 7652, International Optical Design Conference 2010, 76522C (9 September 2010); https://doi.org/10.1117/12.871356

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