Chemically responsive hydrogel with nanoparticle enhanced detection for small biomolecules

Soame Banerji; Wei Peng; Yoon-Chang Kim; Karl S. Booksh

doi:10.1117/12.854610

23 April 2010 Chemically responsive hydrogel with nanoparticle enhanced detection for small biomolecules

Soame Banerji, Wei Peng, Yoon-Chang Kim, Karl S. Booksh

Proceedings Volume 7674, Smart Biomedical and Physiological Sensor Technologies VII; 76740A (2010) https://doi.org/10.1117/12.854610
Event: SPIE Defense, Security, and Sensing, 2010, Orlando, Florida, United States

Abstract

A surface plasmon resonance (SPR) sensor to quantify glucose using a molecularly imprinted polymer was developed. The polymer was prepared by crosslinking poly(allylamine) in the presence of glucose phosphate, monobarium salt (GPS-Ba) and attached to a thin film of gold (50 nm) which had been sputtered on top of a glass slide, via amide coupling. Upon removal of the template, this sensor was used to detect glucose in human urine in physiologically significant levels (1-20 mg/ml). Signal enhancement of the glucose sensor was made possible by incorporating gold nanoparticles in the polymer.

Citation Download Citation

Soame Banerji, Wei Peng, Yoon-Chang Kim, and Karl S. Booksh "Chemically responsive hydrogel with nanoparticle enhanced detection for small biomolecules", Proc. SPIE 7674, Smart Biomedical and Physiological Sensor Technologies VII, 76740A (23 April 2010); https://doi.org/10.1117/12.854610

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available