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14 May 2010 Digital holography for second harmonic microscopy: application to 3D-tracking of nanoparticles
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Abstract
Retrieval of the amplitude and phase of electromagnetic waves made digital holographic microscopy (DHM) capable of revealing morphological details at ultrahigh resolution in the order of a few nanometers only and precisely measuring the refractive index across a sample (e.g. cell or neuron). In short,DHM added a new dimension to optical imaging,whic h explains why it is such an excellent instrument for metrological,but also for biological applications. We believe that DHM is,b y nature,ideally suited for nonlinear microscopy. In this work,w e review the advantages of DHM for nonlinear microscopy and present its application to determination of the axial position of nonlinear nanoparticles capable of second harmonic generation.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Etienne Shaffer and Christian Depeursinge "Digital holography for second harmonic microscopy: application to 3D-tracking of nanoparticles", Proc. SPIE 7715, Biophotonics: Photonic Solutions for Better Health Care II, 771505 (14 May 2010); https://doi.org/10.1117/12.854289
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