18 May 2010 Implantable reflectance pulse transit time blood pressure sensor with oximetry capability
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Abstract
We present a novel implantable multi-wavelength reflectance sensor for the measurement of blood pressure with pulse transit time (PTT). Continuous long-term monitoring of blood pressure and arterial oxygen saturation is vital for medical diagnostics and the ensuing therapy of cardiovascular diseases. Conventional cuff-based blood pressure monitors do not provide continuous data and put severe constraints on the patients' daily lives. An implantable sensor would eliminate such problems. The new biocompatible sensor is placed subcutaneously on blood perfused tissue. The PTT is calculated by photoplethysmograms and the ECG-signal, that is recorded with intracorporal electrodes. In addition, the sensor detects the arterial oxygen saturation. An ensuing spectralphotometric analysis of the light intensity changes delivers data on the concentration of dysfunctional hemoglobin derivatives. Experimental measurements showed a clear correlation between the estimated PTT and the systolic blood pressure reference. These initial results demonstrate the potential of the sensor as part of an fully implantable sensor system for the longterm-monitoring of cardiovascular parameters.
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J. Fiala, J. Fiala, R. Gehrke, R. Gehrke, M. Theodor, M. Theodor, P. Bingger, P. Bingger, K. Förster, K. Förster, C. Heilmann, C. Heilmann, F. Beyersdorf, F. Beyersdorf, H. Zappe, H. Zappe, A. Seifert, A. Seifert, "Implantable reflectance pulse transit time blood pressure sensor with oximetry capability", Proc. SPIE 7715, Biophotonics: Photonic Solutions for Better Health Care II, 77152Q (18 May 2010); doi: 10.1117/12.854512; https://doi.org/10.1117/12.854512
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