You have requested a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Neither SPIE nor the owners and publishers of the content make, and they explicitly disclaim, any express or implied representations or warranties of any kind, including, without limitation, representations and warranties as to the functionality of the translation feature or the accuracy or completeness of the translations.
Translations are not retained in our system. Your use of this feature and the translations is subject to all use restrictions contained in the Terms and Conditions of Use of the SPIE website.
15 September 2010Images of arterial tissues using catheter swept source optical coherence tomography
Optical coherence tomography images of arterial samples harvested from asymptomatic pigs and from lipid-rich
Watanabe heritable hyperlipidemic rabbits were acquired using a fiber catheter-based swept-source optical coherence
tomography system (OCT). A quadrature Mach-Zehnder interferometer based on multi-port fiber couplers and a
semiconductor optical amplifier (SOA) were employed in the swept-source optical coherence tomography system. The
improvement of signal to noise ratio as a result of incorporating the SOA into the configuration translated in an increase
of the penetration depth. A fiber probe ending in a fiber ball lens was developed for the arterial imaging. The images
acquired by this system offer the possibility to investigate anatomical details located under the surface of the artery such
as the intima, media, and adventitia layers (from lumen side) of the blood vessel wall , as well as morphological features
specific to artherosclerotic plaques such as lipid pools, fibrous caps, macrophage accumulations and calcified. This
report indicates that our improved catheter-based swept source OCT is a potential tool for in vivo intravascular imaging.
The alert did not successfully save. Please try again later.
Youxin Mao, Costel Flueraru, Shoude Chang, Dan P. Popescu, M. G. Sowa, "Images of arterial tissues using catheter swept source optical coherence tomography," Proc. SPIE 7750, Photonics North 2010, 77500C (15 September 2010); https://doi.org/10.1117/12.872422