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24 August 2010 A new nanostructured Silicon biosensor for diagnostics of bovine leucosis
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Abstract
In this report we propose a new instrumental method for the biochemical diagnostics of the bovine leucosis through the registration of the formation of the specific immune complex (antigen-antibody) with the help of biosensor based on the nano-structured silicon. The principle of the measurements is based on the determination of the photosensitivity of the surface. In spite of the existed traditional methods of the biochemical diagnostics of the bovine leucosis the proposed approach may provide the express control of the milk quality as direct on the farm and during the process raw materials. The proposed variant of the biosensor based on the nano-structured silicon may be applied for the determination of the concentration of different substances which may form the specific complex in the result of the bioaffine reactions. A new immune technique based on the nanostructured silicon and intended for the quantitative determination of some toxic substances is offered. The sensitivity of such biosensor allows determining T-2 mycotoxin at the concentration of 10 ng/ml during several minutes.
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A. I. Luchenko, M. M. Melnichenko, N. F. Starodub, and O. M. Shmyryeva "A new nanostructured Silicon biosensor for diagnostics of bovine leucosis", Proc. SPIE 7759, Biosensing III, 77590Q (24 August 2010); https://doi.org/10.1117/12.860235
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