Towards stable trapping of single macromolecules in solution

Arijit Kumar De; Debjit Roy; Debabrata Goswami

doi:10.1117/12.862364

27 August 2010 Towards stable trapping of single macromolecules in solution

Arijit Kumar De, Debjit Roy, Debabrata Goswami

Proceedings Volume 7762, Optical Trapping and Optical Micromanipulation VII; 776203 (2010) https://doi.org/10.1117/12.862364
Event: SPIE NanoScience + Engineering, 2010, San Diego, California, United States

Abstract

The implementation of high instantaneous peak power of a femtosecond laser pulse at moderate time-averaged power (~10 mW) to trap latex nanoparticles, which is otherwise impossible with continuous wave illumination at similar power level, has recently been shown [De, A. K., Roy, D., Dutta, A. and Goswami, D. "Stable optical trapping of latex nanoparticles with ultrashort pulsed illumination", Appd. Opt., 48, G33 (2009)]. However, direct measurement of the instantaneous trapping force/stiffness due to a single pulse has been unsuccessful due to the fleeting existence (~100 fs) of the laser pulse compared with the much slower time scale associated with the available trapping force/stiffness calibration techniques, as discussed in this proceeding article. We also demonstrate trapping of quantum dots having dimension similar to macromolecules.

Citation Download Citation

Arijit Kumar De, Debjit Roy, and Debabrata Goswami "Towards stable trapping of single macromolecules in solution", Proc. SPIE 7762, Optical Trapping and Optical Micromanipulation VII, 776203 (27 August 2010); https://doi.org/10.1117/12.862364

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