Dynamic deformation of a soft particle by dual-trap optical tweezers

Sebastien Rancourt-Grenier; Ming-Tzo Wei; Jar-Jin Bai; Arthur Chiou; Paul Bareil; Pierre-Luc Duval; Yunlong Sheng

doi:10.1117/12.860262

27 August 2010 Dynamic deformation of a soft particle in dual-trap optical tweezers

Sebastien Rancourt-Grenier; Ming-Tzo Wei; Jar-Jin Bai; Arthur Chiou; Paul Bareil; Pierre-Luc Duval; Yunlong Sheng

Author Affiliations +

Proceedings Volume 7762, Optical Trapping and Optical Micromanipulation VII; 77621H (2010) https://doi.org/10.1117/12.860262
Event: SPIE NanoScience + Engineering, 2010, San Diego, California, United States

Abstract

A dual-trap optical tweezers is used for deforming the red blood cell (RBC) in suspension and studying its elasticity. The radiation force is applied directly to the cell without physical contact. The 3D radiation stress distribution was computed by ray tracing, the generalized Lorentz-Mie theory with the T-matrix and the FDTD via the Maxwell stress tensor. The 3D deformation of the cells was computed with the elastic membrane theory. The calculated deformation can fit to experimental data resulting in cell's elasticity coefficient. The static approach is valid only for small deformation (5- 10%). For a large deformation such as that of the RBC, we consider re-distribution of the radiation stress on the morphologically deformed cell. This stress re-distribution in turn induces subsequent deformation of the deformed cell and new stress re-distribution. The recursive process continues until a final equilibrium state is achieved. This iterative computation was implemented with the finite element method using the COMSOL^TM multi-physics models. The deformation results can fit to the experimental data for cell's deformation up to 20%.

Citation Download Citation

Sebastien Rancourt-Grenier, Sebastien Rancourt-Grenier, Ming-Tzo Wei, Ming-Tzo Wei, Jar-Jin Bai, Jar-Jin Bai, Arthur Chiou, Arthur Chiou, Paul Bareil, Paul Bareil, Pierre-Luc Duval, Pierre-Luc Duval, Yunlong Sheng, Yunlong Sheng, } "Dynamic deformation of a soft particle in dual-trap optical tweezers", Proc. SPIE 7762, Optical Trapping and Optical Micromanipulation VII, 77621H (27 August 2010); doi: 10.1117/12.860262; https://doi.org/10.1117/12.860262

ACCESS THE FULL ARTICLE

PERSONAL SIGN IN
Full access may be available with your subscription

Email or Username Forgot your username?

Password Forgot your password?

Show

Remember Email/Username on this computer

Remember Password

No SPIE account? Create an account
or Institutional Sign In via Shibboleth

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $14.40

Non-members: $18.00 ADD TO CART

Show All Keywords

Keywords/Phrases

Search In:

Publication Years