27 August 2010 Investigation of limited-view image reconstruction in optoacoustic tomography employing a priori structural information
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Abstract
Optoacoustic tomography (OAT) is an emerging ultrasound-mediated biophotonic imaging modality that has exciting potential for many biomedical imaging applications. There is great interest in conducting B-mode ultrasound and OAT imaging studies for breast cancer detection using a common transducer. In this situation, the range of tomographic view angles is limited, which can result in distortions in the reconstructed OAT image if conventional reconstruction algorithms are applied to limited-view measurement data. In this work, we investigate an image reconstruction method that utilizes information regarding target boundaries to improve the quality of the reconstructed OAT images. This is accomplished by developing boundary-constrained image reconstruction algorithm for OAT based on Bayesian image reconstruction theory. The computer-simulation studies demonstrate that the Bayesian approach can effectively reduce the artifact and noise levels and preserve the edges in reconstructed limited-view OAT images as compared to those produced by a conventional OAT reconstruction algorithm.
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Chao Huang, Chao Huang, Alexander A. Oraevsky, Alexander A. Oraevsky, Mark A. Anastasio, Mark A. Anastasio, } "Investigation of limited-view image reconstruction in optoacoustic tomography employing a priori structural information", Proc. SPIE 7800, Image Reconstruction from Incomplete Data VI, 780004 (27 August 2010); doi: 10.1117/12.861005; https://doi.org/10.1117/12.861005
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