9 November 2010 Monte Carlo simulation of non-invasive glucose measurement based on FMCW LIDAR
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Proceedings Volume 7845, Optics in Health Care and Biomedical Optics IV; 784518 (2010); doi: 10.1117/12.870348
Event: Photonics Asia 2010, 2010, Beijing, China
Abstract
Continuous non-invasive glucose monitoring is a powerful tool for the treatment and management of diabetes. A glucose measurement method, with the potential advantage of miniaturizability with no moving parts, based on the frequency modulated continuous wave (FMCW) LIDAR technology is proposed and investigated. The system mainly consists of an integrated near-infrared tunable semiconductor laser and a detector, using heterodyne technology to convert the signal from time-domain to frequency-domain. To investigate the feasibility of the method, Monte Carlo simulations have been performed on tissue phantoms with optical parameters similar to those of human interstitial fluid. The simulation showed that the sensitivity of the FMCW LIDAR system to glucose concentration can reach 0.2mM. Our analysis suggests that the FMCW LIDAR technique has good potential for noninvasive blood glucose monitoring.
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Bing Xiong, Wenxiong Wei, Nan Liu, Jian-Jun He, "Monte Carlo simulation of non-invasive glucose measurement based on FMCW LIDAR", Proc. SPIE 7845, Optics in Health Care and Biomedical Optics IV, 784518 (9 November 2010); doi: 10.1117/12.870348; https://doi.org/10.1117/12.870348
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KEYWORDS
Glucose

Tissue optics

LIDAR

Scattering

Monte Carlo methods

Light scattering

Mie scattering

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